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Voltage channels open and close in response to changes in membrane potential.

What do voltage-gated channels do?

  • Voltage-gated ion channels are membrane-integral proteins that allow certain inorganic ions to flow through cell membranes. They play a crucial part in the electrical signaling process used by excitable cells like neurons, opening and closing in response to variations in transmembrane voltage.
  • Ion channels that are triggered by changes in the electrical membrane potential close to the channel are known as voltage-gated ion channels. The membrane potential modifies the channel proteins' shape, controlling how they open and close.
  • When a chemical ligand, such as a neurotransmitter, attaches to the protein, ligand-gated ion channels open. Changes in membrane potential cause voltage channels to open and shut.

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