Which of the following activities are most closely associated with natural killer cells? Select all that apply: a. production of TNF-α
b. lysis of virus-infected cells
c. phagocytosis of bacteria
d. release of reactive oxygen intermediates
e. production of IFN-γ

Respuesta :

production of IFN-γ is the most closely associated with natural killer cells. Thus, Option e. is the correct one.

If you analyze carefully, you would find out that type I interferon (IFN) production is the key event developing from the recognition of host DNA and consequent activation of signaling pathways by all DNA sensors. The type I IFN family consists of various IFN-α and single IFN-β. IFN-γ is produced predominantly by natural killer cells (NK) as well as by natural killer T cells (NKT) as part of the innate immune response, and also by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity starts developing as part of the adaptive immune response.

If you want to know more about natural killer cells:

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