The correct sequence formation of tubercules in order to test your understanding of the pathogenesis of tuberculosis are as follow:
- Mycobacteria are engulfed by alveolar macrophage.
- Mycobacteria proliferate within the infected macrophage. Additional immune cells arrive and macrophages become foamy.
- A fibrous capsule surrounds the macrophage.
- Infected macrophage lyse releasing mycobacteria and creating caseous necrosis.
- The tubercule ruptures releasing mycobacteria.
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