Warning: Black Box for Antipsychotics
Antipsychotic-treated elderly people with dementia-related psychosis had a higher probability of passing away.
The FDA mandates the most serious medicine label warnings, known as "black box" warnings. Abilify has two. One cautions against aripiprazole use in young adults, adolescents, and children due toideation. The second cautions that elderly dementia patients who take the medication run an increased chance of passing away.
Antipsychotics of the first generation are the traditional antipsychotics that inhibit the dopamine pathway by inhibiting the D2 receptors and decrease dopaminergic neurotransmission.
Atypical antipsychotics of the second generation, which partially block dopamine receptors and have other side effects like serotonin, are also known as second generation antipsychotics.
Antipsychotics of the second generation are more successful at lessening the signs and symptoms of schizophrenia while also enhancing general quality of life.
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