Respuesta :
Neisseria meningitidis, which causes meningococcal meningitis, can trigger sporadic disease outbreaks by capsular switching.
In many regions of the world, meningococcal meningitis is a dangerous infection that is linked to high rates of mortality and morbidity. The bacteria is well-known for transforming its genetic material to change its capsular polysaccharide from one serogroup to another in response to immunological pressure during a major immunization campaign. Meningococcal meningitis can modify its capsular phenotype through a genetic mechanism known as capsular switching, and as a result, epidemics can start or continue using this strategy. Due to immunologic escape from immunity to the original serogroup, which occurs as a result, the escape serogroup takes control and spreads like wildfire.
Hence, Neisseria meningitidis uses capsular switching to overcome immune system of individual.
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