Professional antigen-presenting cells (APCs) are immune cells specialized in presenting antigens to T cells. The main types of professional APCs are dendritic cells (DC), macrophages, and B cells.
Dendritic cells have the broadest spectrum of antigen presentation and are required for the activation of naive T cells. DCs present antigens to both helper T cells and cytotoxic T cells. It can also perform cross-presentation, the process of presenting exogenous antigens on MHC class I molecules to cytotoxic T cells.
Antigen-presenting cells are the first cells to interact with antigens and are involved in the processing, presentation, and interaction of antigens with the immune system. T cell antigen receptor.
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