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Cephalosporins are a group of broad-spectrum semisynthetic beta-lactam antibiotics. Cephalosporins kill bacteria by inhibiting the synthesis of peptidoglycan.
Cephalosporins are fungicides that directly kill bacteria. They do this by interfering with the bacterial cell wall structure. Cephalosporins are divided into five generations based on when they were developed. Each generation is generally effective against a specific type of bacteria.
Cephalosporins have low toxicity and are generally safe. The most common side effects of cephalosporins are nausea, vomiting, loss of appetite, and abdominal pain. Cephalosporins and other β-lactam antibiotics cause proximal tubular necrosis in humans and experimental animals. Selective toxicity for PCT occurs due to high intracellular concentrations achieved by active transport by organic anion transporters.
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Cephalosporins have low toxicity and are generally safe. The most common side effects of cephalosporins are nausea, vomiting, loss of appetite, and abdominal pain.
Cephalosporins are fungicides that directly kill bacteria. They do this by interfering with the bacterial cell wall structure. Cephalosporins are divided into five generations based on when they were developed. Each generation is generally effective against a specific type of bacteria.
Cephalosporins and other β-lactam antibiotics cause proximal tubular necrosis in humans and experimental animals. Selective toxicity for PCT occurs due to high intracellular concentrations achieved by active transport by organic anion transporters.
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