Correct me if wrong but i believe separation of church and state gave us the right to practice freely without any goverment interference. As i know machiavelli was alive from mid 1400's to late 1500s and was influenced along with his family on the new spirit of theĀ Renaissance that put reason over faith so because of that im assuming he would not approve because he was power greedy. Hope my answer helped thats a hard question to be answering