A person has a bone fracture and takes a painkiller that causes blood vessel constriction. Why might this pain killer actually slow bone healing? Specifically describe how the drug would affect the three stages of bone healing.

Blood vessels are needed throughout a spongy bone but most may not contain true Haversian. Cells provide blood with trabeculae which contain
osteocytes. and osteocytes which operate roles such as providing blood vessels and nerves.
in the trabeculae are nourished directly from the blood circulating through the cavities.
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Histrionicus Histrionicus · Answer 2 · 2020-01-06T12:53:00+01:00

Answer:

Painkillers affects the healing of bones negatively and slow down the healing process. One should be careful what class of painkillers one takes for sprains, ruptured tendons and fractures.

Inflammation is one of the major step of the bone healing whic is affected by the painkillers like NSAIDs that inhibits COX-2 that is helpful in impair bone fracture due to the stop the endochondral ossification pathway.

These painkiller inhibits the important gene expression that leads to slow bone repair.