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These are damaging effects on the liver. This is because the liver is meant to act basically as a filter for your body, so if you drink too much, it's overloaded with toxic substances that it has to filter out, and this leads to damage.
The given blank can be filled with liver.
Drinking excessive alcohol can enhance the threat of developing liver disease and results in irreparable destruction to this vital part of the body. In fact, alcohol abuse is the prime cause of the 25 percent of the death due to liver disease.
The initial symptoms of liver disease due to alcohol abuse are abdominal pains, vomiting, fatigue, diarrhea, nausea, and fatigue.