MODS Patho: release of __ due to activation of _ system, vascular endothelial damage due to toxins, inflammatory mediators - Hypotension - Hypoperfion - _ - becae platelets and tissue thromboplastin activated - ___ state a) Anti-inflammatory mediators, Nervo, Hypoxia, Coagulation, Inflammatory b) Pro-inflammatory mediators, Immune, Hyperoxia, Bleeding, Hypercoagulable c) Inflammatory mediators, Immune, Hyperoxia, Coagulation, Hypocoagulable d) Pro-inflammatory mediators, Inflammatory, Hypoxia, Bleeding, Hypercoagulable

In MODS (Multiple Organ Dysfunction Syndrome) pathophysiology, the release of pro-inflammatory mediators due to activation of the inflammatory system can lead to vascular endothelial damage caused by toxins. This damage, along with the effects of inflammatory mediators, can result in hypotension and hypoperfusion. As a consequence, hypoxia occurs. Additionally, platelets and tissue thromboplastin may become activated, leading to a hypercoagulable state. Bleeding can also be a complication due to dysfunctional coagulation in MODS