Difference between anemia of chronic disease and iron deficiency anemia?
a) Anemia of chronic disease is typically normocytic-normochromic, whereas iron deficiency anemia is usually microcytic-hypochromic.
b) Anemia of chronic disease is characterized by low serum iron and low total iron-binding capacity (TIBC), whereas iron deficiency anemia typically presents with low serum iron and high TIBC.
c) Anemia of chronic disease is caused by inflammation and cytokine-mediated suppression of erythropoiesis, while iron deficiency anemia results from insufficient iron stores for erythropoiesis.
d) Anemia of chronic disease often exhibits a blunted response to iron therapy, whereas iron deficiency anemia typically improves with iron supplementation.