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Lethargy and fatigue are similar in that they both involve a lack of energy or motivation, but they have different underlying causes and manifestations.

Fatigue is a general feeling of tiredness or lack of energy, often resulting from physical or mental exertion, lack of sleep, or stress. It can be temporary and relieved by rest, and is a common symptom of various medical conditions.

Lethargy, on the other hand, is a state of drowsiness or apathy, often accompanied by a lack of interest or enthusiasm. It can be a symptom of an underlying medical or psychological issue, such as depression, anemia, or hypothyroidism.

In summary, fatigue is a feeling of physical or mental tiredness, while lethargy is a state of drowsiness and lack of motivation or interest. If you are experiencing persistent feelings of fatigue or lethargy, it's important to consult with a healthcare professional to determine the underlying cause and receive appropriate treatment.