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Both organisms are composed of cells, the basic unit of life, with each cell surrounded by a cell membrane. The biggest difference between prokaryotes and eukaryotes is that eukaryotes have a nucleus. They also have other membrane structures called organelles.
The main difference between prokaryotic cells and eukaryotic cells is that eukaryotic cells have a nucleus and prokaryotic cells do not. Also eukaryotic cells contain membrane-bound organelles, while prokaryotic cells do not. The eukaryotic cells are also larger in size, indicating that they are more complex.

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