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The impact that The Jungle had on the public after reading it was so great that a federal investigation had to be launched simply due to the uproar it had caused. The setting that Sinclair chose was vital in creating that massive uproar in society.
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Based on historical perspective, the most important effect of the publication of The Jungle is that it "exposes the appalling working conditions in the meat-packing industry."

The Jungle book

The Jungle was written by Upton Sinclair and released in 1906. The novel reveals the difficult situations and exploited lives of immigrants in Chicago and other industrialized areas in the U.S.

This publication led the US government to investigate the meatpacking industries and establish regulations.

Hence, in this case, it is concluded that the correct answer is "it exposes the appalling working conditions in the meat-packing industry."

Learn more about Upton Sinclair here: https://brainly.com/question/6499593