The answer is 2
The Spanish colonization in South America started with the arrival of Christopher Columbus in the Caribbean and consistently expanded through the following years to half of South America, what now is Argentina, Bolivia, Chile, Colombia, Ecuador, Paraguay, Peru, Uruguay and Venezuela (NUMBER 2), most of Central American and part of North America, more specifically in Mexico.
The Columbus arrival meant a great change in how the indigenous tribes lived, the Spanish came to control and dominate their whole lifestyles and take their natural resources to send it to the Spanish crown.
