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Sickle cell anemia is due to a homozygous recessive genotype and leads to deformed red blood cells and an inability to properly transport oxygen throughout the body. However, in a heterozygous context, it is beneficial as it leads to resistance to malaria.

The homozygous recessive traits are those traits, which occur due to the inheritance of two recessive alleles of coding for a particular genotype.  

The real life example of a homozygous recessive trait is sickle cell anemia. In this condition, the inheritance of the recessive alleles for sickle shape red blood cells leads to change in the shape of the red blood cells to sickle like. Due to the changes in the shape of red blood cells, it is not able to carry the oxygen in the blood, which leads to the anemia condition.  


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