Indigestion can be a side effect of Mrs. Cherry’s medication for her heart condition specifically digoxin. The pharmacist may not recommend any pain relievers such as aspirin, ibuprofen or naproxen sodium because it can worsen her indigestion. She may purchase antacids to alleviate the symptoms of indigestion and if indigestion persist, she must visit her doctor for he/she might give another medication for your heart condition. Therefore, she should consider any drug interaction between digoxin and indigestion medication.