How are mutations prevented during dna replication?

DNA polymerase checks DNA for errors. DNA polymerase checks DNA for errors by breaking the hydrogen bonds between the paired nitrogen bases in the DNA molecule. This causes the molecule to separate into two individual strands.

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agis agis · Answer 2 · 2019-04-23T13:56:40+02:00

Answer:

By proofreading activity of DNA polymerase.

Explanation:

Mutations are defined as permanent, inherited changes in the nucleotide sequence of genetic material. Mutations can be caused by errors during the DNA replication, when the enzyme DNA polymerase adds a wrong nucleotide to the growing DNA strand.

When a wrong nucleotide or base is detected (by proof-reading activity of DNA polymerase) in the growing chain, DNA replications halts and the incorrect base is removed by the enzyme's exonuclease activity. Then, DNA polymerase again starts to replicate the DNA, using its polymerizing activity.

Thus, the errors can be prevented during DNA replication by DNA polymerase as it shows both polymerizing, exonuclease and as well as proof-reading activity.