Answer: Option A, Santiago de los caballeros
Explanation: The sentence, in English, is:
"Is the name from which was know before to be called Antigua Guatemala..."
And the options are:
a. Santiago de los Caballeros
b. Volcán de Agua
c. El Camino de Santiago
d. Los Caballeros
During the colonial times, Antigua Guatemala was called "Santiago de los Caballeros de Guatemala", Shortened to "santiago de los Caballeros", so the right answer would be option A.