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Sarah and Jane were playing basketball. They collided and fell. Sarah’s knee was lightly bruised. Jane’s elbow was scratched, causing a little blood to ooze out. After a few days, Jane observed pus formation around the scratch on her elbow, while Sarah’s knee was fine. The pus formation on Jane’s elbow is a result of . The receptors on the sensed the pain that Jane experienced.

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What happens on Jane's elbow?
when a skin is scratched, the internal medium of the body enter directly in contact with the external environment, this could lead bacteria (saprophytic bacteria which lives on the skin, or bacteria from another source) it will provoke an inflammatory reaction to these pathogens and so, a pus will be formed (generally composed by dead neutrophils and purulent bacteria).

What happened on Sarah's knee?
The knee was just bruised, there's not skin scratching, it is still intact, so bacteria cannot go into the body through this injury. It just takes colors (red, blue, then yellow due to the rupture of capillaries which release blood, then will be degraded in bilirubin)

Blank 1: Inflammation

Blank 2: Dermis

Explanation: Inflammation is a response of the body when any foreign particle or any pathogen enters the body and comes in contact with the layers of skin blow epidermis or even blood. In such a response, the immune cells reach the site of bruise and kill the pathogens. The pain in the affected region is a part of inflammation response. And pus is the way of removal of dead pathogenic cells from the body. The pain receptors are present in the dermis.