Which equation, when graphed, has x-intercepts at (2, 0) and (4, 0) and a y-intercept of (0, –16)?

f(x) = –(x – 2)(x – 4)
f(x) = –(x + 2)(x + 4)
f(x) = –2(x – 2)(x – 4)
f(x) = –2(x + 2)(x + 4)