Respuesta :

taskmasters


Sickle cell anemia is caused by an abnormal hemoglobin in red blood cells. hemoglobin is the red pigment found in red blood cells for carrying oxygen.

The abnormality arises from a genetic mutation in the DNA gene that codes for the  beta chain of the protein called globin of which hemoglobin is made of.

In the beta chain, the sixth amino acid called glutamine is replaced by another one called valine.

This one change in the amino acids cause the hemoglobin protein  to behave abnormally, causing  red blood cells to lose their normal spherical shape and become bent like a sickle, hence the name "sickle cell" anemia

ShyzaSling

Sickle cell anemia is a hereditary disease which provides less oxygen to cells due to a change in the shape of red blood cells which fails to carry oxygen to cells.  

In sickle cell anemia, the effected or mutated part is the beta gene that normally makes hemoglobin but due to the mutation in the amino acid, the protein formed is defected and fails to perform its normal function.

As mentioned above, it is a heredity diseases and pass from generations to generations.


Otras preguntas