The correct response would be C. "Me lastime a la muneca" roughly translates to "I hurt my wrist". The answer C "Ay, que lastima!" means, "Ouch, that would hurt" or "Aw, how bad". It's what you say when someone gets hurt and you empathize with them. D, means "Does your leg hurt?", and your leg would not hurt if you injured your wrist.
