Calculate the H positive from the pH equation: pH equals -log (H positive). This would be 10 to the -6.49. Let's call the acid HA. To calculate Ka in this equation, Ka equals H positive times A- over HA. HA is going to be the 0 0121. So, Ka=(10^-6.49)^2/0.0121. This equals 1.05*10^-13/0.0121. Ka then equals 8.65*10^-12.