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TOPOISOMERASE

There are various function of DNA toposisomerase such as:

1.accessing DNA- this happens during transcription and replication, DNA must be unwound for this to happen, Topoisomerase I make a single break to create an access.

2. Removing DNA super coils- Topoisomerase prevents DNA to be supercoiled, this happens during transcription of DNA to RNA

3. Strand breakage- It can introduce single strand breaks that are required for DNA to be exchanged to adjacent chromosomes.