Hydrogen Bonding will effect the boiling point the most. Let's take an example Butane a four carbon unsaturated organic compound with molecular formula C₄H₁₀ and boiling point -1 °C.
H₃C-CH₂-CH₂-CH₃
Now, replace one hydrogen on terminal carbon with -OH group and convert it into Butanol.
H₃C-CH₂-CH₂-CH₂-OH
The Boiling point of Butanol is 117.7 °C. This increase in boiling point is due to formation of hydrogen bondings between the molecules of Butanol.
