2-methyl-3-hexyn-2-ol can be prepared from Acetylene by treating Acetylene with NaNH₂ followed by CH₃CH₂Br, then treating the intermediate with NaNH₂ followed by acetone and then doing aqueous workup. NaNH₂ acts as base and abstracts proton from acetylene as the terminal alkynes are acidic in nature. While acetone on reduction gives tertiary alcohol.
