sickle cell anemia is known to run in a family. A pedigree chart for this family is shown below.

The parents are shown at the top and from left to right appear as a half-shaded circle labeled 1 next to a half-shaded square labeled 2. The two are connected by a straight line. Below the parent pair is a vertical straight line connecting to the next row of circles and squares which are the offspring. Starting from left an unshaded square labeled 1, half-shaded circle labeled 2, another half-shaded circle labeled 3, and a completely shaded square are shown labeled 4. All of these are also connected by a horizontal straight line.

What best describes offspring 4?

A. A female carrier of the disease
B. A female having the disease
C. A male carrier of the disease
D. A male having the disease

Sickle cell anemia is a disease due to mutation in the protein hemoglobin found in red blood cells which results in the red blood cells being unable to transport oxygen efficiently round the body.

The pedigree shows that an unshaded square or circle is sickle cell free, a half-shaded shape is a carrier while a fully shaded shape have the disease.

Females are represented by circles while males are represented by squares.

Since the square labelled 4 is fully shaded, it represents a male having the disease.

Learn more about sickle cell disease at: https://brainly.com/question/3895081