Pressurized steam is a simple and effective sterilization
method. Medical autoclaves are devices that uses steam to sterilize materials
and equipment.
Pressurized steam or Autoclaving typical conditions
are at a temperature of 121 degrees C, 15 psi for 15 minutes or longer to kill endospores.
To
destroy prions, conditions of autoclaving is at 132 degrees C for 4.5 hours.