Why is pyridine included in the reaction of an acid chloride and an amine or alcohol? Pyridine will deprotonate the amine or alcohol, making it a better nucleophile. Pyridine will neutralize the acid by-product of the reaction. Pyridine will protonate the carbonyl of the acid chloride, making it more reactive. Pyridine will absorb the heat of the reaction.
Pyridine will neutralize the acid by-product of the reaction.
Explanation:
In the esterifications, hydrochloric acid is released as a by-product that reacts directly with the pyridine in the medium to give the pyridine hydrochloride.
