Select which of the following are mechanisms used by pathogens to avoid host defenses and to successfully colonize the host.

-Producing siderophores to obtain iron from the host for growth.
- Producing IgA proteases for avoiding secretory IgA.
-Avoiding secretory IgA by rapid turnover of pili.
-Producing adhesions for damaging host cells.
-Producing toxic substances to suppress host responses.