HURRY PLEASE

Which of the Following statements correctly describes the process of GPCR signaling?

1. The GPCR activation is reversible after the signal of the ligand diminishes.
2. The membrane-embedded enzyme uses GTP as a secondary messenger to initiate gene expression.
3. The Ligand attaches to both the GPCR and the membrane-embedded enzyme to activate the GPCR pathway.
4. The ligand-bound GPCR septs a GTP molecule to an enzyme in the membrane and switches it into an active state