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Macduff first becomes weary of Macbeth in Act II, scene iii, when Macbeth announces he has killed the guards. Earlier in the play, Macbeth and Lady Macbeth smear blood and leave bloody daggers by King Duncan's guards to frame the guards for King Duncan's murder. Macbeth says: "O, yet I do repent me of my fury, / That I did kill them," and Macduff's response is: "Wherefore did you so?" Macduff's response implies that he is initially suspicious -- why would Macbeth murder the only two witnesses available to explain what happened to the King? From this quote, the audience can derive that Macduff sees through Macbeth's lies. Macduff then decides he will "to Fife" (Fife is where Macduff is Thane) instead of Macbeth's coronation. He refuses to see Macbeth crowned as King of Scotland when Macduff believes Macbeth has been false.
The context clues show that Macduffs attitude toward Macbeth was because he announced that he killed the guards.
What are context clues?
Context clues are the hints that are given by the author in a literary work.
In this case, the context clues show that Macduffs attitude toward Macbeth was because he announced that he killed the guards. This made Macduffs weary.
In conclusion, Macduffs attitude toward Macbeth changed when. he was aware that he killed the guards.
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https://brainly.com/question/26349330