According to question, All ambassadorial appointments, which are made at the president's discretion, require the advise and permission of the Senate.
According to the American Constitution, the President "shall have power, by and with the advice and consent of the Senate, to establish Treaties, provided two-thirds of the Senators present approve" (Article II, section 2). Treaties are binding agreements that are incorporated into international law.
The president is the commander in chief. He has the power to appoint ambassadors, sign treaties, and make executive agreements.
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